Evolutionary genetics of the human Rh blood group system
نویسندگان
چکیده
منابع مشابه
THE Rh BLOOD GROUP SYSTEM
T he Rh blood group system is one of the most polymorphic and antigenic blood group systems. It is second only to ABO in importance in blood transfusion and is well known as a primary cause of hemolytic disease of the fetus and newborn (HDFN). The principal antigen is D, and the terms Rh positive and Rh negative refer to the presence or absence of D antigen. Caucasians of European extraction ha...
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The Rh blood group system is one of the most polymorphic and immunogenic systems known in humans. In the past decade, intense investigation has yielded considerable knowledge of the molecular background of this system. The genes encoding 2 distinct Rh proteins that carry C or c together with either E or e antigens, and the D antigen, have been cloned, and the molecular bases of many of the anti...
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In April I965, anti-Doa, an antibody defining a 'new' red cell antigen, was reported (Swanson, Polesky, Tippett, and Sanger, I965). The present paper records the results of tests with anti-Doa on samples received in this unit from October I964 until April I966. Anti-Doa reacts best by the antiglobulin test on papainized cells, but only a minority of otherwise good antiglobulin sera are suitable...
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Blood Transfus 2007; 5: 50-57 © SIMTI Servizi Srl The Rhesus factor is clinically the most important protein-based blood group system. With 49 antigens so far described, it is the largest of all 29 blood group systems. The unusually large number of Rhesus antigens is attributable to its complex genetic basis. The antigens are located on two Rhesus proteins RhD and RhCE and are produced by diffe...
متن کاملMolecular-genetic variance of RH blood group system within human population of Bosnia and Herzegovina.
There are two major theories for inheritance of Rh blood group system: Fisher - Race theory and Wiener theory. Aim of this study was identifying frequency of RHDCE alleles in Bosnian - Herzegovinian population and introduction of this method in screening for Rh phenotype in B&H since this type of analysis was not used for blood typing in B&H before. Rh blood group was typed by Polymerase Chain ...
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ژورنال
عنوان ژورنال: Human Genetics
سال: 2012
ISSN: 0340-6717,1432-1203
DOI: 10.1007/s00439-012-1147-5